Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration
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منابع مشابه
Increase in NF-κB-sensitive miRNA-146a and miRNA-155 in multiple sclerosis (MS) and pro-inflammatory neurodegeneration
Deidre J. Devier, Jesus F. Lovera and Walter J. Lukiw* 1 Department of Cell Biology and Anatomy, Louisiana State University Health Sciences Center, New Orleans, LA, USA 2 Department of Neurology, Louisiana State University Health Sciences Center, New Orleans, LA, USA 3 Neuroscience Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA, USA 4 Department of Opht...
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Background: Oral Lichen Planus (OLP) is a chronic autoimmune disease that could be considered as a potential premalignant status. Objective: To evaluate the miRNA-146a and miRNA-155 expression levels in patients with oral Lichen planus lesions compared to healthy subjects with normal oral mucosa. Methods: Forty patients with oral lichen planus and 18 healthy age and gender-matched controls were...
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James M. Hill , Christian Clement, Yuhai Zhao and Walter J. Lukiw* 1 Departments of Microbiology and Pharmacology, Louisiana State University Health Science Center, New Orleans, LA, USA 2 LSU Neuroscience Center and Department of Ophthalmology, Louisiana State University Health Science Center, New Orleans, LA, USA 3 Infectious Diseases, Experimental Therapeutics and Human Toxicology Lab, Depart...
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Single-nucleotide polymorphisms (SNPs) in miRNAsmay alter its expression levels or processing and contribute to susceptibility to a wide range of diseases. Our study aimed to evaluate the possible association between miRNA-146a rs2910164 and miRNA-499 rs3746444 polymorphisms and susceptibility to pulmonary tuberculosis (PTB) in a sample of Iranian population. This case- control study was perfor...
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Background & objectives: Nuclear Factor kappa B (NF-κB), a master switch transcription factor, plays a critical role in the progression and development of hyperglycemia-induced microangiopathy. Hyperglycemia activates NF-κB, and subsequently increases pro-inflammatory cytokines such as TNF-α, IL-6 and IL-1β leading to development of inflammation. Some new studies have revealed the involvement o...
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ژورنال
عنوان ژورنال: Frontiers in Molecular Neuroscience
سال: 2015
ISSN: 1662-5099
DOI: 10.3389/fnmol.2015.00005